| 中文名称: |
橙花醇 |
| 英文名称: |
Nerol |
| 产品分类: |
天然产物 |
| CAS号: |
106-25-2 |
| 分子式: |
C10H18O |
| 分子量: |
154.25 |
*产品基础信息:
【产品中文名称】橙花醇;
【产品英文名称】Nerol;
【纯度指标】98.59%;
【品牌】TargetMol;
【CAS号】106-25-2;
【浓度】;
Product Introduction
Bioactivity
| 名称 | Nerol |
| 描述 | Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart. |
| 动物实验 | Guinea pigs were sacrificed by decapitation and hearts were removed and isolated left atrium mounted vertically in an organ baths containing Tyrode's solution of the following composition (mM): NaCl 120, KCl 2.7, MgCl2 0.9, NaHCO3 11.9, CaCl2 1.37, glucose 5.5, NaH2PO4 0.4, pH 7.4. The atria preparations were subsequently connected to Grass FI'-03 force displacement transducers to record changes in atrial contractile force. Each muscle was stretched to the length at which contractile force was maximal (1.0 gf). The atria were electrically paced at 1 Hz with pulses of 1.5 ms duration and stimulated by 70 V pulses. All preparations were allowed to equilibrate for 30 min until complete mechanical stabilization had been achieved. Nerol ( 97%) was freshly solubilized in 0.5% DMSO and cumulatively added to bath chambers. After each observation, muscles were washed several times and allowed to recover for 30 minutes until their mechanical function completely returned to control values. DMSO at this concentration did not show any significant effect on the variables measured (data not shown, n = 5). |
| 体内活性 | Nerol主要通过阻断L型Ca2+通道减少Ca2+的流入,从而减轻了哺乳动物心脏中ouabain引发的心律失常的严重程度。 |
| 存储条件 | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+90% Saline : 10 mg/mL (64.83 mM), Solution. DMSO : 250 mg/mL (1620.75 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (12.97 mM), Sonication is recommended.
|
| 关键字 | ROS | ReactiveOxygenSpecies | Reactive Oxygen Species | Nerol | NEL | MitochondrialMetabolism | Mitochondrial Metabolism | mitochondrial | Inhibitor | inhibit | Fungal | EndogenousMetabolite | Endogenous Metabolite | dysfunction | Calcium | Apoptosis | Antifungal |
| 相关产品 | Guanidine hydrochloride | Glycerol | Aceglutamide | Malic acid | Calcium Propionate | DL-Lysine | Sucrose | Guanidine thiocyanate | Gluconate Calcium | Thymidine | D(+)-Raffinose pentahydrate | Ethyl linoleate |
| 相关库 | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Anti-Fungal Compound Library | Ancient Chinese Classical Formulas Compound Library | Miao medicine Compound Library | Bitter Compound library | Flavor Natural Product library | Traditional Chinese Medicine Monomer Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Anti-infective Natural Product Library |





























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